Anti-CLU Antibody (N-term)
Boster Bio Anti-CLU Antibody (N-term) (Catalog # A00590-2) . Tested in WB, Flow Cytometry, IHC-P-Leica application (s) . This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The protein encoded by this gene appears to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. However, the function of this protein is unknown. Three transcript variants encoding different isoforms have been found for this gene, and one of them is secreted and processed into a mature form.
Synonyms
Clusterin, Aging-associated gene 4 protein, Apolipoprotein J, Apo-J, Complement cytolysis inhibitor, CLI, Complement-associated protein SP-40, Ku70-binding protein 1, NA1/NA2, Testosterone-repressed prostate message 2, TRPM-2, Clusterin beta chain, ApoJalpha, Complement cytolysis inhibitor a chain, Clusterin alpha chain, ApoJbeta, Complement cytolysis inhibitor b chain, CLU, APOJ, CLI, KUB1
Gene Name
CLU
UniProt
P10909
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This CLU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human CLU.
Clonality
Polyclonal
Tissue Specificity
Detected in blood plasma, cerebrospinal fluid, milk, seminal plasma and colon mucosa. Detected in the germinal center of colon lymphoid nodules and in colon parasympathetic ganglia of the Auerbach plexus (at protein level) . Ubiquitous. Detected in brain, testis, ovary, liver and pancreas, and at lower levels in kidney, heart, spleen and lung.
Applications
WB, Flow Cytometry, IHC-P-Leica
Field of Research
Cancer, Cardiovascular, Cell Biology, Metabolism, Signal Transduction, Immunology, Innate Immunity, Mitochondria
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
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Molecular Weight
52495 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
[Isoform 1]: Secreted. Note=Can retrotranslocate from the secretory compartments to the cytosol upon cellular stress. [Isoform 6]: Cytoplasm. Note=Keeps cytoplasmic localization in stressed and unstressed cell.
Available Sizes
Frequently Asked Questions
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