What is the catalog number for Anti-EPOR Antibody (C-term)?

The catalog number for Anti-EPOR Antibody (C-term) is A00427-3.

Is Anti-EPOR Antibody (C-term) in stock?

Anti-EPOR Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-EPOR Antibody (C-term)?

The safety data sheet for Anti-EPOR Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A00427-3.

Anti-EPOR Antibody (C-term)

Boster Bio Anti-EPOR Antibody (C-term) (Catalog # A00427-3) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Background

Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Synonyms

Erythropoietin receptor, EPO-R, EPOR

Gene Name

EPOR

UniProt

P19235

Host

Rabbit

Reactivity

Human

Immunogen

This EPOR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 470-504 amino acids from the C-terminal region of human EPOR.

Clonality

Polyclonal

Tissue Specificity

Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow Isoform EPOR-T is the most abundant from in early-stage erythroid progenitor cells

Applications

WB, Flow Cytometry

Field of Research

Cardiovascular, Immunology, Signal Transduction, Stem Cells

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.