Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Vimentin Antibody

Boster Bio Anti-Vimentin Antibody (Catalog # A00235-1) . Tested in WB, IF, Flow Cytometry, IHC-P-Leica application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL) -derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.

Synonyms

Vimentin, VIM

Gene Name

VIM

UniProt

P08670

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Vimentin antibody is generated from rabbits immunized with human Vimentin recombinant protein.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.

Applications

WB, IF, Flow Cytometry, IHC-P-Leica

Field of Research

Cancer, Developmental Biology, Neuroscience, Signal Transduction, Viral process, Host-Virus Interaction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

Molecular Weight

53652 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

Rabbit IgG

Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix {ECO:0000250|UniProtKB:P31000}. Cell membrane {ECO:0000250|UniProtKB:P20152}

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

HnRNP M Antibody
8C10693-AAT 50 µg

HnRNP M Antibody

Sign In for Pricing
View Details
HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF647 conjugate, 0.1mg/mL
BNC473066-500 1x 500 µL

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
ETFB (NM_001985) Human Over-expression Lysate
LC419607 20 µg

ETFB (NM_001985) Human Over-expression Lysate

Sign In for Pricing
View Details
Cops7b Mouse Gene Knockout Kit (CRISPR)
KN503688 1 Kit

Cops7b Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
PRRT2 Mouse Monoclonal Antibody [Clone ID: OTI9H8]
CF809867 100 µg

PRRT2 Mouse Monoclonal Antibody [Clone ID: OTI9H8]

Sign In for Pricing
View Details
FITC Anti-Mouse CD3 Antibody[17A2]
E-AB-F1013UC-01 25 µg

FITC Anti-Mouse CD3 Antibody[17A2]

Sign In for Pricing
View Details