Anti-CBS Antibody (Center)
Selected Variant
A00130-2-01
Size: 80 µL
Boster Bio Anti-CBS Antibody (Center) (Catalog # A00130-2) . Tested in WB, IHC-P-Leica, Flow Cytometry, IF application (s) . This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.
Synonyms
Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase, CBS
Gene Name
CBS
UniProt
P35520
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from the Central region of human CBS.
Clonality
Polyclonal
Tissue Specificity
In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney
Applications
WB, IHC-P-Leica, Flow Cytometry, IF
Field of Research
Cancer, Metabolism, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
239817742050632523974653
Molecular Weight
60587 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Cytoplasm. Nucleus
Prediction Reactivity
Monkey
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