What is the catalog number for Anti-KLF4 Antibody (C-term)?

The catalog number for Anti-KLF4 Antibody (C-term) is A00120-2.

Is Anti-KLF4 Antibody (C-term) in stock?

Anti-KLF4 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-KLF4 Antibody (C-term)?

The safety data sheet for Anti-KLF4 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A00120-2.

Anti-KLF4 Antibody (C-term)

Boster Bio Anti-KLF4 Antibody (C-term) (Catalog # A00120-2) . Tested in WB, Flow Cytometry, IF application (s) . This antibody reacts with Human.

Product Specifications

Background

KLF4 is a transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.

Synonyms

Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF

Gene Name

KLF4

UniProt

O43474

Host

Rabbit

Reactivity

Human

Immunogen

This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-421 amino acids from the C-terminal region of human KLF4.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, IF

Field of Research

Cancer, Cardiovascular, Developmental Biology, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.