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TRH Thyrotropin Releasing Hormone Human protein

162264

Product Specifications

Synonyms

Thyroliberin; TRH; MGC125964; MGC125965; Protirelin; TRF

Gene Name

TRH

UniProt

P20396

Reactivity

Human

Tissue Specificity

Hypothalamus. Expressed in the hair follicle epithelium (at protein level) .

Sequence

[object Object]

Purification

Greater than 98.2% as determined by analysis by RP-HPLC.

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Reconstitution

It is recommended to reconstitute the lyophilized Thyroliberin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Function

Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes.

Shipping Conditions

Available

Storage Conditions

Lyophilized Protirelin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TRH should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.

Other Gene Names

Pro-thyrotropin-releasing hormone

Subcellular Location

Secreted.

Available Sizes

Frequently Asked Questions

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