Anti-GDE1 Antibody

Boster Bio Anti-GDE1 Antibody (Catalog # M10470) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Has glycerophosphoinositol phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity) .

Synonyms

Glycerophosphodiester phosphodiesterase 1, 3.1.4.44, Membrane-interacting protein of RGS16, RGS16-interacting membrane protein, GDE1, MIR16

Gene Name

GDE1

UniProt

Q9NZC3

Host

Mouse

Reactivity

Human

Immunogen

This GDE1 antibody is generated from a mouse immunized with a recombinant protein from the human region of human GDE1.

Clonality

Monoclonal

Clone

Clone: 2021CT823.61.7

Tissue Specificity

Widely expressed.

Applications

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Dilution

WB: 1:2000

Function

Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity) . Hydrolyzes glycerophospho-N-acylethanolamines to N- acylethanolamines in the brain and participates in bioactive N- acylethanolamine biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N- oleoylethanolamine (an anorexic) . In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl- lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity (By similarity) . Has little or no activity towards glycerophosphocholine (By similarity) .

Molecular Weight

37718 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

IgG1, κ

Subcellular Location

Cell membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Note=Perinuclear vesicles and cell membrane {ECO:0000250|UniProtKB:Q9JL55}