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Anti-SH3PXD2B Antibody (C-Term)

Boster Bio Anti-SH3PXD2B Antibody (C-Term) (Catalog # M08324) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Background

Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity) .

Synonyms

SH3 and PX domain-containing protein 2B, Adapter protein HOFI, Factor for adipocyte differentiation 49, Tyrosine kinase substrate with four SH3 domains, SH3PXD2B, FAD49, KIAA1295, TKS4

Gene Name

SH3PXD2B

UniProt

A1X283

Host

Rabbit

Reactivity

Human

Immunogen

This SH3PXD2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 596-628 amino acids from human SH3PXD2B.

Clonality

Polyclonal

Tissue Specificity

Expressed in fibroblasts.

Applications

WB, Flow Cytometry

Field of Research

Developmental Biology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity) .

Molecular Weight

101579 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M08324

Product MSDS

https://www.bosterbio.com/msds?sku=M08324

Fragment

Rabbit IgG

Subcellular Location

Cytoplasm. Cell projection, podosome. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC-transformed cells.

Available Sizes

Curated Selection

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