Anti-METTL14 Antibody (N-Term)
Boster Bio Anti-METTL14 Antibody (N-Term) (Catalog # M07389) . Tested in IF, WB, IHC-P application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.
Synonyms
N6-adenosine-methyltransferase subunit METTL14, 2.1.1.62, Methyltransferase-like protein 14, METTL14, KIAA1627
Gene Name
METTL14
UniProt
Q9HCE5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This METTL14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the human region of human METTL14.
Clonality
Polyclonal
Applications
IF, WB, IHC-P
Field of Research
Cell Biology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
24316715244074212571967129348140273733372728119427627798273733372728119429348140243167152440742125719671
Molecular Weight
52150 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Nucleus
Prediction Reactivity
Bovine
Available Sizes
Frequently Asked Questions
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