Anti-REG3G Antibody
Boster Bio Anti-REG3G Antibody (Catalog # M05473) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.
Product Specifications
Background
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
Synonyms
Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 16.5 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B
Gene Name
REG3G
UniProt
Q6UW15
Host
Mouse
Reactivity
Human
Immunogen
This REG3G antibody is generated from a mouse immunized with a recombinant protein of human REG3G.
Clonality
Monoclonal
Clone
Clone: 1790CT313.66.2
Tissue Specificity
Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta
Applications
WB, IHC-P
Field of Research
Inflammation, Immunology
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota.
Molecular Weight
19330 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG1, k
Subcellular Location
Secreted {ECO:0000250|UniProtKB:P42854}. Cytoplasm {ECO:0000250|UniProtKB:P42854}
Available Sizes
Frequently Asked Questions
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