Anti-GLS2 Antibody
Boster Bio Anti-GLS2 Antibody (Catalog # M05334) . Tested in WB, IHC-P application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Synonyms
Glutaminase liver isoform, mitochondrial, GLS, 3.5.1.2, L-glutaminase, L-glutamine amidohydrolase, GLS2, GA
Gene Name
GLS2
UniProt
Q9UI32
Host
Mouse
Reactivity
Human, Mouse
Immunogen
This GLS2 antibody is generated from a mouse immunized with a recombinant protein of human GLS2.
Clonality
Monoclonal
Clone
Clone: 1758CT879.217.60
Tissue Specificity
Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas.
Applications
WB, IHC-P
Field of Research
Metabolism, Signal Transduction, Mitochondria
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha- ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.
Molecular Weight
66323 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG1, k
Subcellular Location
Mitochondrion.
Available Sizes
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