Anti-PDCD1LG2 Antibody (N-term)

Boster Bio Anti-PDCD1LG2 Antibody (N-term) (Catalog # M03295-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .

Synonyms

Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2

Gene Name

PDCD1LG2

UniProt

Q9BQ51

Host

Mouse

Reactivity

Human

Immunogen

This PDCD1LG2 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 40-75 amino acids from the N-terminal region of human PDCD1LG2.

Clonality

Monoclonal

Clone

Clone: 2011CT241.19.54

Tissue Specificity

Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus

Applications

WB, IHC-P

Field of Research

Immunology

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .

Molecular Weight

30957 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M03295-1

Product MSDS

https://www.bosterbio.com/msds?sku=M03295-1

Fragment

IgG1, κ

Subcellular Location

[Isoform 3]: Secreted [Isoform 1]: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9WUL5, ECO:0000305|PubMed:15340161}

Available Sizes

Curated Selection

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