Anti-RAB27A Antibody
Boster Bio Anti-RAB27A Antibody (Catalog # M01608-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.
Product Specifications
Background
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Synonyms
Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27
Gene Name
RAB27A
UniProt
P51159
Host
Mouse
Reactivity
Human
Immunogen
This RAB27A antibody is generated from a mouse immunized with a recombinant protein of human RAB27A.
Clonality
Monoclonal
Clone
Clone: 1590CT813.266.26
Tissue Specificity
Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta Detected in melanocytes, and in most tumor cell lines examined Expressed in cytotoxic T-lymphocytes (CTL) and mast cells
Applications
WB, Flow Cytometry
Field of Research
Signal Transduction, Lysosome
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
30771381
Molecular Weight
24868 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG1, k
Subcellular Location
Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065) . Localizes to endosomal exocytic vesicles (PubMed:17237785) .
Available Sizes
Frequently Asked Questions
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