Anti-Profilin-1 Antibody
Boster Bio Anti-Profilin-1 Antibody (Catalog # M01480-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
Synonyms
Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1
Gene Name
PFN1
UniProt
P07737
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This Profilin-1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-140 amino acids from the human region of human Profilin-1.
Clonality
Polyclonal
Tissue Specificity
Expressed in epididymis (at protein level) .
Applications
WB, Flow Cytometry
Field of Research
Cancer, Cell Biology, Neuroscience, Signal Transduction, Viral process
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
Molecular Weight
15054 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
Rabbit IgG
Subcellular Location
Cytoplasm, cytoskeleton.
Prediction Reactivity
Bovine
Available Sizes
Frequently Asked Questions
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