What is the catalog number for Anti-GLS Antibody (C-Term)?

The catalog number for Anti-GLS Antibody (C-Term) is M01272-1.

Is Anti-GLS Antibody (C-Term) in stock?

Anti-GLS Antibody (C-Term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GLS Antibody (C-Term)?

The safety data sheet for Anti-GLS Antibody (C-Term) is available here: https://www.bosterbio.com/msds?sku=M01272-1.

Anti-GLS Antibody (C-Term)

Boster Bio Anti-GLS Antibody (C-Term) (Catalog # M01272-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.

Synonyms

Glutaminase kidney isoform, mitochondrial, GLS, K-glutaminase, L-glutamine amidohydrolase, GLS, GLS1, KIAA0838

Gene Name

GLS

UniProt

O94925

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GLS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 555-587 amino acids from human GLS.

Clonality

Polyclonal

Tissue Specificity

Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle.

Applications

Field of Research

Metabolism, Neuroscience, Signal Transduction, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Dilution

WB: 1:2000

Function

305758543023972130970188

Molecular Weight

73461 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

Rabbit IgG

Subcellular Location

[Isoform 1]: Mitochondrion {ECO:0000250|UniProtKB:P13264}. Cytoplasm, cytosol. Note=The 74-kDa cytosolic precursor is translocated into the mitochondria and processed via a 72-kDa intermediate to yield the mature 68- and 65-kDa subunits {ECO:0000250|UniProtKB:P13264} [Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix {ECO:0000250|UniProtKB:P13264} Note=Produced by the proteolytic processing of the 74-kDa cytosolic precursor. {ECO:0000250|UniProtKB:P13264}