What is the catalog number for Anti-TXN Antibody?

The catalog number for Anti-TXN Antibody is M01219-2.

Is Anti-TXN Antibody in stock?

Anti-TXN Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TXN Antibody?

The safety data sheet for Anti-TXN Antibody is available here: https://www.bosterbio.com/msds?sku=M01219-2.

Anti-TXN Antibody

Boster Bio Anti-TXN Antibody (Catalog # M01219-2) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

Synonyms

Thioredoxin, Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN, TRDX, TRX, TRX1

Gene Name

TXN

UniProt

P10599

Host

Mouse

Reactivity

Human

Immunogen

This antibody is generated from a mouse immunized with a recombinant protein from human.

Clonality

Monoclonal

Clone

Clone: 1850CT339.14.1

Applications

Field of Research

Cell Biology, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Dilution

WB: 1:2000

Function

217649017182577190322341640802017606900910802911118054

Molecular Weight

11737 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

IgG1, k

Subcellular Location

Nucleus. Cytoplasm. Secreted Note=Translocates from the cytoplasm into the nucleus after phorbol 12- myristate 13-acetate induction (PMA) (PubMed:9108029) . Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054) . Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054) . Secreted by a leaderless secretory pathway (PubMed:1332947) .