Anti-MGMT Antibody
Boster Bio Anti-MGMT Antibody (Catalog # M01012-2) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.
Product Specifications
Background
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Synonyms
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, MGMT
Gene Name
MGMT
UniProt
P16455
Host
Mouse
Reactivity
Human
Immunogen
This MGMT antibody is generated from a mouse immunized with a recombinant protein.
Clonality
Monoclonal
Clone
Clone: 1527CT158.87.44
Applications
WB, Flow Cytometry
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Molecular Weight
21646 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG1, k
Subcellular Location
Nucleus.
Available Sizes
Frequently Asked Questions
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