What is the catalog number for Anti-SMAD1 Antibody?

The catalog number for Anti-SMAD1 Antibody is M00728-3.

Is Anti-SMAD1 Antibody in stock?

Anti-SMAD1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-SMAD1 Antibody?

The safety data sheet for Anti-SMAD1 Antibody is available here: https://www.bosterbio.com/msds?sku=M00728-3.

Anti-SMAD1 Antibody

Boster Bio Anti-SMAD1 Antibody (Catalog # M00728-3) . Tested in WB, IHC-P, IF application (s) . This antibody reacts with Human.

Product Specifications

Background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.

Synonyms

Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1, SMAD1, BSP1, MADH1, MADR1

Gene Name

SMAD1

UniProt

Q15797

Host

Mouse

Reactivity

Human

Immunogen

This SMAD1 antibody is generated from a mouse immunized with a recombinant protein between 20-330 amino acids from human SMAD1.

Clonality

Monoclonal

Clone

Clone: 1356CT119.18.55

Tissue Specificity

Ubiquitous. Highest expression seen in the heart and skeletal muscle

Applications

WB, IHC-P, IF

Field of Research

Cancer, Developmental Biology, Signal Transduction, Stem Cells, Anti-Wnt-Pathway (plus Lgr5) Antibodies

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

93355043366754333667543

Molecular Weight

52260 Da

Shipping Conditions

Available

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Fragment

IgG1, k

Subcellular Location

Cytoplasm. Nucleus Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271) . Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271) . Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity) {ECO:0000250|UniProtKB:P70340, ECO:0000269|PubMed:15647271}