Anti-HAVCR2 Antibody
Boster Bio Anti-HAVCR2 Antibody (Catalog # M00657-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.
Product Specifications
Background
Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1) -mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.
Synonyms
Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3, HAVCR2, TIM3, TIMD3
Gene Name
HAVCR2
UniProt
Q8TDQ0
Host
Mouse
Reactivity
Human
Immunogen
This HAVCR2 antibody is generated from a mouse immunized with a recombinant protein of human HAVCR2.
Clonality
Monoclonal
Clone
Clone: 1827CT151.74.68
Tissue Specificity
Expressed in T-helper type 1 (Th1) lymphocytes. Expressed on regulatory T (Treg) cells after TCR stimulation. Expressed in dendritic cells and natural killer (NK) cells. Expressed in epithelial tissues. Expression is increased on CD4+ and CD8+ T-cells in chronic hepatitis C virus (HCV) infection. In progressive HIV-1 infection, expression is up-regulated on HIV-1-specific CD8 T-cells
Applications
WB, Flow Cytometry
Field of Research
Immunology, Inflammation, Innate Immunity
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
2482577711823861145560052433774126492563248388571628692024337741235552612232345322383801
Molecular Weight
33394 Da
Shipping Conditions
Available
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG2b, k
Subcellular Location
Membrane; Single-pass type I membrane protein. Cell junction. Cell membrane. Note=Localizes to the immunological synapse between CD8+ T-cells and target cells
Available Sizes
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