Anti-Human HLA-DR CD74 Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated

Boster Bio Anti-Human HLA-DR CD74 Monoclonal Antibody PE-Cy7 Conjugated, Flow Validated (Catalog# FC01340-PE-Cy7) . Tested in Flow Cytometry application (s) . This antibody reacts with Human, Rhesus monkey, Cynomolgus monkey, Baboon.

Product Specifications

Synonyms

HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74; CD74; DHLAG

Gene Name

CD74

UniProt

P01903

Host

Mouse

Reactivity

Human, Rhesus monkey, Cynomolgus monkey, Baboon

Immunogen

Human B lymphocytes

Clonality

Monoclonal

Clone

Clone: Clone: L243

Conjugation

PE-Cy7

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Immunology

Purification

Affinity column chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

User needs to optimize the dilution ratio for this antibody.

Form

Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA

Function

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Molecular Weight

33516 MW

Shipping Conditions

Available

Storage Conditions

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Fragment

IgG2a, k

Other Gene Names

HLA class II histocompatibility antigen gamma chain

Subcellular Location

Cell membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.