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Anti-human CD5 Monoclonal Antibody APC Conjugated, Flow Validated

Boster Bio Anti-human CD5 Monoclonal Antibody APC Conjugated, Flow Validated (Catalog# FC00480-APC) . Tested in Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Background

CD5, also known as T1 or LEU1, is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. It is mapped to 11q12.2. Although CD5 can be found on both T cells and B cells, T cells express higher levels of CD5 than B cells. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. CD5 is upregulated on T cells upon strong activation. In the thymus, there is a correlation with CD5 expression and strength of the interaction of the T cell towards self-peptides. Nevertheless, CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.

Synonyms

T-cell surface glycoprotein CD5; Lymphocyte antigen T1/Leu-1; CD5; CD5; LEU1

Gene Name

CD5

UniProt

P06127

Host

Mouse

Reactivity

Human

Immunogen

Human peripheral blood lymphocytes

Clonality

Monoclonal

Clone

Clone: Clone: OKT1

Conjugation

APC

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage

Purification

Protein A purified

Sensitivity

5ul per sample

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

User needs to optimize the dilution ratio for this antibody.

Form

Liquid

Function

May act as a receptor in regulating T-cell proliferation.

Molecular Weight

54578 MW

Shipping Conditions

Available

Storage Conditions

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=FC00480-APC

Product MSDS

https://www.bosterbio.com/msds?sku=FC00480-APC

Fragment

IgG1, k

Other Gene Names

T-cell surface glycoprotein CD5

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

T-cell surface glycoprotein CD5

Available Sizes

Curated Selection

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