Anti-Human CD86 Monoclonal Antibody APC Conjugated, Flow Validated

Boster Bio Anti-Human CD86 Monoclonal Antibody APC Conjugated, Flow Validated (Catalog# FC00220-APC) . Tested in Flow Cytometry application (s) . This antibody reacts with Human, Rhesus monkey, Cynomolgus monkey, Baboon.

Product Specifications

Synonyms

T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD86; CD86; CD28LG2

Gene Name

CD86

UniProt

P42081

Host

Mouse

Reactivity

Human, Rhesus monkey, Cynomolgus monkey, Baboon

Immunogen

B-lymphoblastoid cell line ARH 77

Clonality

Monoclonal

Clone

Clone: Clone: BU63

Conjugation

APC

Tissue Specificity

Expressed by activated B-lymphocytes and monocytes.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, Cell Type Markers, Hematopoietic Progenitors, Host-Virus Interaction, Immunology, Interspecies Interaction, Lymphoid, Microbiology, Myeloid, Stem Cells, T Cells

Purification

Affinity column chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

User needs to optimize the dilution ratio for this antibody.

Form

Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA

Function

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T- cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.