IL-17 Interleukin-17 Rat Recombinant Protein
Selected Variant
PROTQ61453-01
Size: 5 µg
Interleukin-17A Rat Recombinant produced in E. coli is a homodimeric, non-glycosylated polypeptide chain having a molecular mass of 30 kDa. The IL-17A Rat is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
CTLA-8; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; Interleukin-17A
Gene Name
IL17A
UniProt
Q61453
Reactivity
Rat
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Bioactivity
The ED50 as determined by dose-dependent induction of IL-6 by mouse NIH 3T3 fibroblasts is 0.44-0.66ng/ml.
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
It is recommended to reconstitute the lyophilized Interleukin Rat 17A in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function
Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
Shipping Conditions
Available
Storage Conditions
Lyophilized Interleukin Rat 17A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Rat IL17 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.
Other Gene Names
Interleukin-17A
Subcellular Location
Secreted.
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