IHH Indian Hedgehog Human Recombinant Protein
IHH Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 176 amino acids and having a molecular mass of 19.8kDa. The IHH is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
Indian hedgehog protein; IHH; HHG-2; BDA1
Gene Name
IHH
UniProt
Q14623
Reactivity
Human
Tissue Specificity
Expressed in embryonic lung, and in adult kidney and liver.
Source
Escherichia coli
Sequence
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Purification
Greater than 95.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Bioactivity
50
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
2
Function
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity) .
Shipping Conditions
Available
Storage Conditions
Lyophilized IHH although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IHH should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Other Gene Names
Indian hedgehog protein
Subcellular Location
Indian hedgehog protein N-product: Cell membrane
Available Sizes
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