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IHH Indian Hedgehog Human Recombinant Protein

IHH Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 176 amino acids and having a molecular mass of 19.8kDa. The IHH is purified by proprietary chromatographic techniques.

Product Specifications

Synonyms

Indian hedgehog protein; IHH; HHG-2; BDA1

Gene Name

IHH

UniProt

Q14623

Reactivity

Human

Tissue Specificity

Expressed in embryonic lung, and in adult kidney and liver.

Source

Escherichia coli

Sequence

[object Object]

Purification

Greater than 95.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

Bioactivity

50

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Reconstitution

2

Function

Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity) .

Shipping Conditions

Available

Storage Conditions

Lyophilized IHH although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IHH should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Other Gene Names

Indian hedgehog protein

Subcellular Location

Indian hedgehog protein N-product: Cell membrane

Available Sizes

Frequently Asked Questions

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