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BD-1 Beta Defensin-1 Mouse Recombinant Protein

BD 1 Mouse Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 37 amino acids and having a molecular mass of 4.1 KDa. The BD 1 Mouse is purified by proprietary chromatographic techniques.

Product Specifications

Synonyms

Beta-defensin 1; BD-1; Defensin beta 1; hBD-1; HBD1; HBP1; DEFB1; HBD-1; HBP-1; DEFB101; DEFB-1; MGC51822

Gene Name

DEFB1

UniProt

P56386

Reactivity

Mouse

Tissue Specificity

Detected in kidney.

Source

Escherichia coli

Sequence

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Purification

Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

Bioactivity

Measured by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/ml, corresponding to a specific activity of 1,000-10,000units/mg.

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Reconstitution

2

Function

Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.

Shipping Conditions

Available

Storage Conditions

Lyophilized Mouse BD 1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD 1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Other Gene Names

Beta-defensin 1

Subcellular Location

Secreted

Available Sizes

Frequently Asked Questions

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