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LA/SS-B LA / SS-B Human Recombinant Protein

LA/SS-B Human Recombinant produced in SF9 is a single, glycosylated, polypeptide chain having a calculated molecular mass of 52 kDa, is fused to a hexahistidine purification tag. The LA/SS-B is purified by proprietary chromatographic techniques.

Product Specifications

Synonyms

Lupus La protein; Sjoegren syndrome type B antigen; SS-B; La ribonucleoprotein; La autoantigen; SSB; La; LARP3; LA/SS-B; La (SS-B)

Gene Name

SSB

UniProt

P05455

Reactivity

Human

Source

Sf9 insect cells

Purification

Greater than 95.0% as determined by SDS-PAGE.

Form

Sterile Filtered clear solution.

Function

Binds to the 3' poly (U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590) . In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597) .

Shipping Conditions

Available

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

Other Gene Names

Lupus La protein

Subcellular Location

Nucleus

Available Sizes

Frequently Asked Questions

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