BD-1 Beta Defensin -1 Rat Recombinant Protein
BD-1 Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 37 amino acids and having a molecular mass of 4.1kDa. The BD-1 is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
Beta-defensin 1; BD-1; rBD-1; Defensin beta 1; Defb1
Gene Name
DEFB1
UniProt
O89117
Reactivity
Rat
Tissue Specificity
Highly expressed in kidney.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 95.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Bioactivity
Measured by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/ml.
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
2
Function
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
Shipping Conditions
Available
Storage Conditions
Lyophilized BD-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Other Gene Names
Beta-defensin 1
Subcellular Location
Secreted
Available Sizes
Frequently Asked Questions
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