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BD-4 Beta Defensin-4 Rat Recombinant Protein

BD-4 Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 41 amino acids and having a molecular mass of 4.4kDa. The BD-4 is purified by proprietary chromatographic techniques.

Product Specifications

Synonyms

Beta-defensin 4; BD-4; BD-2; Defensin; beta 4; RBD-2; RBD-4; Defb4; Defb2; Defb3

Gene Name

DEFB4

UniProt

O88514

Reactivity

Rat

Tissue Specificity

Highly expressed in lung.

Source

Escherichia coli

Sequence

[object Object]

Purification

Greater than 97.0% as determined by SDS-PAGE.

Bioactivity

Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 5-50µg/ml.

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Reconstitution

2

Function

Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells.

Shipping Conditions

Available

Storage Conditions

Lyophilized BD-4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PROTO88514

Product MSDS

https://www.bosterbio.com/msds?sku=PROTO88514

Other Gene Names

Beta-defensin 4

Subcellular Location

Secreted

Available Sizes

Curated Selection

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