BD-4 Beta Defensin-4 Rat Recombinant Protein
BD-4 Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 41 amino acids and having a molecular mass of 4.4kDa. The BD-4 is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
Beta-defensin 4; BD-4; BD-2; Defensin; beta 4; RBD-2; RBD-4; Defb4; Defb2; Defb3
Gene Name
DEFB4
UniProt
O88514
Reactivity
Rat
Tissue Specificity
Highly expressed in lung.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 97.0% as determined by SDS-PAGE.
Bioactivity
Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 5-50µg/ml.
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
2
Function
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells.
Shipping Conditions
Available
Storage Conditions
Lyophilized BD-4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD-4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Other Gene Names
Beta-defensin 4
Subcellular Location
Secreted
Available Sizes
Frequently Asked Questions
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