Fractalkine Mouse Recombinant Protein (CX3CL1)
Fractalkine Mouse Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8.7kDa. The CX3CL1 is purified by proprietary chromatographic techniques.
Product Specifications
Synonyms
Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1; Cx3cl1; Cx3c; Fkn; Scyd1; CX3C; ABCD-3; AB030188; AI848747; D8Bwg0439e
Gene Name
CX3CL1
UniProt
O35188
Reactivity
Mouse
Tissue Specificity
Highest levels in brain. Lower levels in kidney, heart and lung. Also found in skeletal muscle and testis.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Bioactivity
50
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
It is recommended to reconstitute the lyophilized CX3CL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (By similarity) . Binds to CX3CR1.
Shipping Conditions
Available
Storage Conditions
Lyophilized CX3CL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CX3CL1 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.
Other Gene Names
Fractalkine
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
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