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Urocortin II, mouse

Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with Ki values of 0.66 nM and >100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca2+/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow.

Product Specifications

Purity

≥95%

Molecular Weight

4152.98

Notes

For research use only.

AA Sequence

VILSLDVPIGLLRILLEQARYKAARNQAATNAQILAHV-NH2

Available Sizes

Frequently Asked Questions

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