FKBP5 FK506 Binding Protein 5 Human Recombinant Protein
FKBP5 Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (Met1-Val457) containing 467 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 52.5kDa.
Product Specifications
Synonyms
FK506 Binding Protein 5; 54 KDa Progesterone Receptor-Associated Immunophilin; 51 KDa FK506-Binding Protein; Androgen-Regulated Protein 6; HSP90-Binding Immunophilin; FK506-Binding Protein 5; PPIase FKBP5; 51 KDa FKBP; FF1 Antigen; EC 5.2.1.8; Rotamase; FKBP-51; FKBP51; FKBP54; AIG6; P54; Peptidylprolyl Cis-Trans Isomerase; T-Cell FK506-Binding Protein; PPIASE; Ptg-10; FKBP-5; FKBP5
Gene Name
FKBP5
UniProt
Q13451
Reactivity
Human
Tissue Specificity
Widely expressed, enriched in testis compared to other tissues.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 90.0% as determined by SDS-PAGE.
Form
Filtered White lyophilized (freeze-dried) powder.
Reconstitution
Prepare about 0.5mg/ml working stock solution with deionized water and let the lyophilized pellet dissolve completely. Filter sterilize your culture media/working solutions containing this non-sterile FKBP5 before using in cell culture.
Function
Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) . Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.
Shipping Conditions
Available
Storage Conditions
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Other Gene Names
Peptidyl-prolyl cis-trans isomerase FKBP5
Subcellular Location
Cytoplasm. Nucleus.
Available Sizes
Frequently Asked Questions
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