Proguanylin Human Recombinant Protein
Proguanylin Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain (a.a 22-115) containing 104 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 11.5kDa (calculated) .
Product Specifications
Synonyms
Guanylin Precursor; Guanylate cyclase activator 2A; Guanylate cyclase-activating protein 1; Gap-IGUCA2; STARA; GUANYLIN
Gene Name
GUCA2A
UniProt
Q02747
Reactivity
Human
Tissue Specificity
Highly expressed in ileum and colon. Found in plasma.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 90.0% as determined by SDS-PAGE.
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
Prepare about 0.5mg/ml working stock solution with deionized water and let the lyophilized pellet dissolve completely. Proguanylin is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Function
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Shipping Conditions
Available
Storage Conditions
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.
Other Gene Names
Guanylin
Subcellular Location
Secreted.
Available Sizes
Frequently Asked Questions
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