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Proguanylin Human Recombinant Protein

Proguanylin Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain (a.a 22-115) containing 104 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 11.5kDa (calculated) .

Product Specifications

Synonyms

Guanylin Precursor; Guanylate cyclase activator 2A; Guanylate cyclase-activating protein 1; Gap-IGUCA2; STARA; GUANYLIN

Gene Name

GUCA2A

UniProt

Q02747

Reactivity

Human

Tissue Specificity

Highly expressed in ileum and colon. Found in plasma.

Source

Escherichia coli

Sequence

[object Object]

Purification

Greater than 90.0% as determined by SDS-PAGE.

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Reconstitution

Prepare about 0.5mg/ml working stock solution with deionized water and let the lyophilized pellet dissolve completely. Proguanylin is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Function

Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.

Shipping Conditions

Available

Storage Conditions

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.

Other Gene Names

Guanylin

Subcellular Location

Secreted.

Available Sizes

Frequently Asked Questions

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