SPRR1B Small Proline-Rich Protein 1B Human Recombinant Protein
SPRR1B Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (a.a 2-89) containing 97 amino acids including a 9 a.a N-terminal His tag. The total molecular mass is 10.9kDa (calculated) .
Product Specifications
Synonyms
Cornifin-B; 14.9 kDa pancornulin; Small proline-rich protein IB; SPR-IB; SPRR1B; SPRR1; GADD33; CORNIFIN
Gene Name
SPRR1B
UniProt
P22528
Reactivity
Human
Tissue Specificity
Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 95.0% as determined by SDS-PAGE.
Form
Filtered White lyophilized (freeze-dried) powder.
Reconstitution
Prepare about 0.5mg/ml working stock solution with deionized water and let the lyophilized pellet dissolve completely. SPRR1B is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Function
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage.
Shipping Conditions
Available
Storage Conditions
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Other Gene Names
Cornifin-B
Subcellular Location
Cytoplasm.
Available Sizes
Frequently Asked Questions
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