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NCL Nucleolin Human Recombinant Protein

Nucleolin Human Recombinant produced in SF9 is a glycosylated, polypeptide chain containing the C-terminal section of the human nucleolin and missing the N-terminal histone-binding part of nucleolin, having a calculated molecular mass of 55,162 Dalton. NCL is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.

Product Specifications

Synonyms

Nucleolin; Protein C23; NCL; C23

Gene Name

NCL

UniProt

P19338

Reactivity

Human

Source

Sf9 insect cells

Purification

Greater than 80.0% as determined by SDS-PAGE.

Form

Sterile Filtered clear solution.

Function

Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

Shipping Conditions

Available

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

Other Gene Names

Nucleolin

Subcellular Location

Nucleus, nucleolus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Available Sizes

Frequently Asked Questions

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