What is the catalog number for LBP Lipopolysaccaride Human Recombinant Protein?

The catalog number for LBP Lipopolysaccaride Human Recombinant Protein is PROTP18428.

Is LBP Lipopolysaccaride Human Recombinant Protein in stock?

LBP Lipopolysaccaride Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for LBP Lipopolysaccaride Human Recombinant Protein?

The safety data sheet for LBP Lipopolysaccaride Human Recombinant Protein is available here: https://www.bosterbio.com/msds?sku=PROTP18428.

LBP Lipopolysaccaride Human Recombinant Protein

The Lipopolysaccharide Binding Protein is produced from human LBP transfected CHO-cells in serum free medium. Before transfection the complete human LBP-cDNA was amplified by PCR and cloned into expression vector p-POL-DHFR. The recombinant Human LBP was purified by his-tag with metal affinity purification with Talon and controlled by SDS page. Showing a 58kDa band on SDS-PAGE. Attention: His-tag has no protease site and can not be split off.

Product Specifications

Synonyms

Lipopolysaccharide-binding protein; LBP; MGC22233

Gene Name

LBP

UniProt

P18428

Reactivity

Human

Tissue Specificity

Detected in blood serum (at protein level) .

Source

CHO cells

Bioactivity

Up to 0.2 μg/ ml LBP mediates binding of FITC-LPS (0.5μg/ml) to CD14+CHO transfectants (FACS) .

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Reconstitution

2

Function

Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:7517398, PubMed:24120359) . Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359) .

Shipping Conditions

Available

Storage Conditions

Lyophilized LBP Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution LBP should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.