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IDE Insulin-Degrading Enzyme Human Recombinant Protein

Selected Variant

PROTP14735-01

Size: 2 µg

IDE Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (Met1-Leu1019) containing 1026 amino acids including a 7 aa His tag at C-terminus. The total calculated molecular mass is 119kDa.

Product Specifications

Synonyms

Insulin-Degrading Enzyme; Abeta-Degrading Protease; Insulin Protease; EC 3.4.24.56; Insulinase; INSULYSIN; Insulysin; EC 3.4.24; IDE

Gene Name

IDE

UniProt

P14735

Reactivity

Human

Source

Escherichia coli

Sequence

[object Object]

Purification

Greater than 95.0% as determined by SDS-PAGE.

Form

Filtered colorless solution.

Function

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Shipping Conditions

Available

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Avoid multiple freeze-thaw cycles.

Other Gene Names

Insulin-degrading enzyme

Subcellular Location

Cytoplasm. Cell membrane. Secreted

Available Sizes

Price

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