IDE Insulin-Degrading Enzyme Human Recombinant Protein
Selected Variant
PROTP14735-01
Size: 2 µg
IDE Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (Met1-Leu1019) containing 1026 amino acids including a 7 aa His tag at C-terminus. The total calculated molecular mass is 119kDa.
Product Specifications
Synonyms
Insulin-Degrading Enzyme; Abeta-Degrading Protease; Insulin Protease; EC 3.4.24.56; Insulinase; INSULYSIN; Insulysin; EC 3.4.24; IDE
Gene Name
IDE
UniProt
P14735
Reactivity
Human
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 95.0% as determined by SDS-PAGE.
Form
Filtered colorless solution.
Function
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
Shipping Conditions
Available
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Avoid multiple freeze-thaw cycles.
Other Gene Names
Insulin-degrading enzyme
Subcellular Location
Cytoplasm. Cell membrane. Secreted
Available Sizes
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