NPPA Natriuretic Peptide A Human Recombinant Protein
NPPA Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain (a.a 26-123) containing 106 amino acids including an 8 a.a N-terminal His tag. The total molecular mass is 11.7kDa (calculated) .
Product Specifications
Synonyms
Natriuretic peptides A; CDD-ANF; Cardiodilatin; CDD; Cardiodilatin-related peptide; CDP; N-terminal proatrial natriuretic peptide; ANP; PND.
Gene Name
NPPA
UniProt
P01160
Reactivity
Human
Source
Escherichia coli
Purification
Greater than 95.0% as determined by SDS-PAGE.
Form
Filtered White lyophilized (freeze-dried) powder.
Reconstitution
Prepare about 0.5mg/ml working stock solution with deionized water and let the lyophilized pellet dissolve completely. NPPA is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Function
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Shipping Conditions
Available
Storage Conditions
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Other Gene Names
Natriuretic peptides A
Subcellular Location
Secreted.
Available Sizes
Frequently Asked Questions
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