TPPP Tubulin Polymerization Promoting Protein Human Recombinant Protein

TPPP Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 229 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 24.9kDa (calculated) .

Product Specifications

Synonyms

Tubulin polymerization-promoting protein; TPPP; 25 kDa brain-specific protein; TPPP/p25; p24; p25-alpha; TPPP1; p25; p25alpha

Gene Name

TPPP

UniProt

O94811

Reactivity

Human

Tissue Specificity

Widely expressed.

Source

Escherichia coli

Sequence

[object Object]

Purification

Greater than 85.0% as determined by SDS-PAGE.

Form

Filtered White lyophilized (freeze-dried) powder.

Reconstitution

Prepare about 0.5mg/ml working stock solution with deionized water and let the lyophilized pellet dissolve completely. TPPP is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Function

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

Shipping Conditions

Available

Storage Conditions

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.