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IL-21 Interleukin-21 Rat Recombinant Protein

Interleukin-21 Rat Recombinant produced in E. coli is a single, non-glycosilated polypeptide chain containing 129 amino acids and having a total molecular mass of 15.2kDa. The Rat IL-21 is purified by proprietary chromatographic techniques.

Product Specifications

Background

Interleukin-21; IL-21; Il21

Synonyms

Interleukin-21; IL-21; Il21

Gene Name

IL21

UniProt

A3QPB9

Host

Rat

Reactivity

Rat

Cross Reactivity

The biological activity is measured by its ability to proliferate activated B cells.

Conjugation

Rat IL-21 was lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Source

Escherichia coli

Sequence

[object Object]

Purification

Greater than 95.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

Bioactivity

The biological activity is measured by its ability to proliferate activated B cells.

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Reconstitution

It is recommended to reconstitute the lyophilized Rat IL21 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Function

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG (1) and IgG (3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T- cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity) . During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity) .

Molecular Weight

https://www.bosterbio.com/media/catalog/product/r/e/recombinant-protein-thumbnail_1.png

Shipping Conditions

Available

Storage Conditions

Lyophilized Rat IL-21 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Rat IL21 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PROTA3QPB9

Product MSDS

https://www.bosterbio.com/msds?sku=PROTA3QPB9

Fragment

Sterile Filtered White lyophilized (freeze-dried) powder.

Other Gene Names

Interleukin-21

Subcellular Location

Secreted

Available Sizes

Curated Selection

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