Mouse R-Cadherin-4 Cdh4 ELISA Kit PicoKine®, Carrier-free

Cadherin-4 is a protein that in humans is encoded by the CDH4 gene. It is mapped to 2 H4; 2 101.86 cM. This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. The encoded protein is involved in retinal angiogenesis during development where it plays a crucial role in the endothelial-astrocyte interactions. Alternative splicing results in multiple transcript variants encoding different isoforms.

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>193</td><td>219</td><td>205</td><td>218</td><td>208</td><td>10.63</td><td>5.1%</td></tr><tr><td>Sample 2</td><td>781</td><td>864</td><td>833</td><td>852</td><td>832</td><td>31.72</td><td>3.8%</td></tr><tr><td>Sample 3</td><td>4510</td><td>4030</td><td>4318</td><td>4174</td><td>4258</td><td>177.58</td><td>4.1%</td></tr></table>*number of samples for each test n=16.

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development.

Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)