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Human SLITRK6 ELISA Kit PicoKine®, Carrier-free

Selected Variant

EK1868-carrier-free

Size: 96 Well With Removable Strips

Human SLITRK6 ELISA Kit PicoKine® (96 Tests). Quantitate Human SLITRK6 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

SLIT and NTRK-like protein 6 is a protein that in humans is encoded by the SLITRK6 gene. It is mapped to 13q31.1. This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>22</td><td>27</td><td>27</td><td>25</td><td>25</td><td>2.04</td><td>8.1%</td></tr><tr><td>Sample 2</td><td>71</td><td>63</td><td>66</td><td>74</td><td>68</td><td>4.27</td><td>6.2%</td></tr><tr><td>Sample 3</td><td>307</td><td>320</td><td>287</td><td>314</td><td>307</td><td>12.42</td><td>4.0%</td></tr></table>*number of samples for each test n=16.

Synonyms

SLIT and NTRK-like protein 6; SLITRK6

Gene Name

SLIT and NTRK like family member 6

Gene ID

84189

UniProt

Q9H5Y7

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: S27-S608

Tissue Specificity

In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, serum and plasma (heparin).

Detection Range

15.6 pg/ml - 1,000 pg/ml

Sensitivity

<10 pg/ml

Function

Regulator of neurite outgrowth required for normal hearing and vision.

Components

Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Specificity

Natural and recombinant human SLITRK6

Anticoagulant

heparin

Subcellular Location

Cell membrane. Single-pass type I membrane protein.

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