Human Matrilin-3 ELISA Kit PicoKine®, Carrier-free

Human Matrilin-3 ELISA Kit PicoKine® (96 Tests). Quantitate Human MATN3 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Matrilin-3 is a protein that in humans is encoded by the MATN3 gene. This gene is mapped to 2p24.1. This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>125</td><td>143</td><td>138</td><td>129</td><td>133</td><td>7.11</td><td>5.3%</td></tr><tr><td>Sample 2</td><td>689</td><td>800</td><td>745</td><td>802</td><td>759</td><td>46.43</td><td>6.1%</td></tr><tr><td>Sample 3</td><td>2209</td><td>2281</td><td>2219</td><td>2542</td><td>2312</td><td>135.20</td><td>5.8%</td></tr></table>*number of samples for each test n=16.

Synonyms

Matrilin-3; MATN3

Gene Name

matrilin 3

Gene ID

4148

UniProt

O15232

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: D29-R486

Tissue Specificity

Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders.

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, serum and plasma (heparin, EDTA).

Detection Range

93.7 pg/ml - 6,000 pg/ml

Sensitivity

<50 pg/ml

Function

Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)