Human FCRL1 ELISA Kit PicoKine®, Carrier-free

Human FCRL1 ELISA Kit PicoKine® (96 Tests). Quantitate Human FCRL1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Fc receptor-like protein 1 is a protein that in humans is encoded by the FCRL1 gene. It is mapped to 1q23.1. This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>42</td><td>40</td><td>42</td><td>45</td><td>42</td><td>1.78</td><td>4.2%</td></tr><tr><td>Sample 2</td><td>182</td><td>167</td><td>169</td><td>161</td><td>169</td><td>7.66</td><td>4.5%</td></tr><tr><td>Sample 3</td><td>837</td><td>797</td><td>842</td><td>900</td><td>844</td><td>36.73</td><td>4.3%</td></tr></table>*number of samples for each test n=16.

Synonyms

Fc receptor-like protein 1; FcR-like protein 1; FcRL1; Fc receptor homolog 1; FcRH1; IFGP family protein 1; Hifgp1; Immune receptor translocation-associated protein 5; CD307a; FCRL1; FCRH1; IFGP1; IRTA5

Gene Name

Fc receptor like 1

Gene ID

115350

UniProt

Q96LA6

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: A17-S307

Tissue Specificity

Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells.

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, serum and plasma (heparin, EDTA).

Detection Range

31.2 pg/ml - 2,000 pg/ml

Sensitivity

<20 pg/ml

Function

May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)