Mouse BMP-6 ELISA Kit PicoKine®, Carrier-free

Mouse BMP-6 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Bmp6 in bone tissue, cell culture supernatants and serum. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. It is mapped to 6p24-p23. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>214</td><td>208</td><td>247</td><td>226</td><td>223</td><td>14.9</td><td>6.6%</td></tr><tr><td>Sample 2</td><td>1829</td><td>1835</td><td>1824</td><td>1804</td><td>1823</td><td>11.64</td><td>0.6%</td></tr><tr><td>Sample 3</td><td>5790</td><td>6282</td><td>6158</td><td>5929</td><td>6039</td><td>191.9</td><td>3.1%</td></tr></table>*number of samples for each test n=16.

Synonyms

Bone morphogenetic protein 6; BMP-6; VG-1-related protein; VGR-1; Bmp6; Bmp-6, Vgr1;

Gene Name

bone morphogenetic protein 6

Gene ID

12161

UniProt

P20722

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: CHO; Immunogen sequence: S372-H510

Tissue Specificity

Expressed in the lung. Low levels seen in the kidney.

Applications

ELISA

Standard

10 ng/tube

Sample Type

bone tissue, cell culture supernatants and serum.

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Function

Induces cartilage and bone formation. .

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)