Mouse Kremen-1 ELISA Kit PicoKine®, Carrier-free

Mouse Kremen-1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Kremen1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>171</td><td>171</td><td>172</td><td>159</td><td>168</td><td>5.35</td><td>3.1%</td></tr><tr><td>Sample 2</td><td>880</td><td>925</td><td>969</td><td>991</td><td>941</td><td>42.6</td><td>4.5%</td></tr><tr><td>Sample 3</td><td>4010</td><td>4034</td><td>3878</td><td>4402</td><td>4081</td><td>194.61</td><td>4.7%</td></tr></table>*number of samples for each test n=16.

Synonyms

Kremen protein 1;Dickkopf receptor;Kringle domain-containing transmembrane protein 1;Kringle-containing protein marking the eye and the nose;Kremen1;Kremen;

Gene Name

Kremen protein 1

Gene ID

84035

UniProt

Q99N43

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: A20-G395

Tissue Specificity

In the adult, widely expressed with high levels in heart, lung, kidney, skeletal muscle and testis. .

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

125 pg/ml - 8,000 pg/ml

Sensitivity

<10 pg/ml

Function

Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). .

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)