Human ADAM8/Ms2 ELISA Kit PicoKine®, Carrier-free

Human ADAM8/Ms2 ELISA Kit PicoKine® (96 Tests). Quantitate Human ADAM8 in cell culture supernatants and serum. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene. ADAM8 is localized to chromosome 10q26.3. This gene encodes a member of the ADAM (a disintegrin and metalloproteinase domain) family. Members of the ADAM family, such as ADAM8, are cell surface proteases involved in remodeling of extracellular matrix, cell migration, and processing of membrane-bound signaling molecules. They are characterized by disintegrin and metalloprotease domains that confer adhesive properties and proteolytic activities, respectively. And the protein encoded by this gene may be involved in cell adhesion duringneurodegeneration.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>143</td><td>150</td><td>153</td><td>145</td><td>147</td><td>3.96</td><td>2.6%</td></tr><tr><td>Sample 2</td><td>493</td><td>533</td><td>465</td><td>527</td><td>504</td><td>27.43</td><td>5.4%</td></tr><tr><td>Sample 3</td><td>1805</td><td>1971</td><td>1907</td><td>1936</td><td>1904</td><td>61.88</td><td>3.2%</td></tr></table>*number of samples for each test n=16.

Synonyms

Disintegrin and metalloproteinase domain-containing protein 8;ADAM 8;3.4.24.-;Cell surface antigen MS2;CD156a;ADAM8;MS2;

Gene Name

Disintegrin and metalloproteinase domain-containing protein 8

Gene ID

101

UniProt

P78325

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: M1-P497

Tissue Specificity

Expressed on neutrophils and monocytes.

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants and serum.

Detection Range

62.5 pg/ml - 4,000 pg/ml

Sensitivity

<10 pg/ml

Function

Possible involvement in extravasation of leukocytes.

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)