Human Relaxin-3/RLN3 ELISA Kit PicoKine®, Carrier-free

Relaxin-3 is a neuropeptide which is highly conserved in species ranging from flies, fish, rodents and humans. It is a member and ancestral gene of the relaxin family of peptides, which includes the namesake hormone relaxin (designated 'H2 relaxin' in humans) which mediates peripheral actions during pregnancy and which was found to relax the pelvic ligament in guinea pigs almost a century ago. The broad distribution of relaxin-3 fibres/RXFP3 within several key neuronal circuits suggests an ability to modulate a broad range of behaviours. This has been confirmed in a growing number of rodent studies, which demonstrate relaxin-3 is able to modulate arousal, the response to stress, feeding/metabolism and memory; and likely plays a role in the generation/regulation of hippocampal theta rhythm.

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>65</td><td>66</td><td>66</td><td>70</td><td>66</td><td>1.92</td><td>2.9%</td></tr><tr><td>Sample 2</td><td>225</td><td>219</td><td>209</td><td>235</td><td>222</td><td>9.43</td><td>4.2%</td></tr><tr><td>Sample 3</td><td>942</td><td>1017</td><td>854</td><td>1030</td><td>960</td><td>70.19</td><td>7.3%</td></tr></table>*number of samples for each test n=16.

Relaxin-3;Insulin-like peptide INSL7;Insulin-like peptide 7;Prorelaxin H3;Relaxin-3 B chain;Relaxin-3 A chain;RLN3;INSL7, RXN3, ZINS4;UNQ6188/PRO20213;

Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)