Human Relaxin 1 ELISA Kit PicoKine®, Carrier-free

Human Relaxin 1 ELISA Kit PicoKine® (96 Tests). Quantitate Human RLN1 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Relaxin 1 is a member of relaxin-like peptide family. Relaxin gene maps to human chromosome 19 near D19Mit23. Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. Relaxin widens the pubic bone and facilitates labor, it also softens the cervix (cervical ripening), and relaxes the uterine musculature. However, its significance may reach much further. Relaxin affects collagen metabolism, inhibiting collagen synthesis and enhancing its breakdown by increasing matrix metalloproteinases. It also enhances angiogenesis and is a potent renal vasodilator.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>144</td><td>125</td><td>144</td><td>133</td><td>136</td><td>8.01</td><td>5.8%</td></tr><tr><td>Sample 2</td><td>819</td><td>759</td><td>734</td><td>688</td><td>750</td><td>47.28</td><td>6.3%</td></tr><tr><td>Sample 3</td><td>2390</td><td>2222</td><td>2307</td><td>2378</td><td>2324</td><td>67.01</td><td>2.8%</td></tr></table>*number of samples for each test n=16.

Synonyms

Prorelaxin H1;Relaxin B chain;Relaxin A chain;RLN1;

Gene Name

Prorelaxin H1

Gene ID

6013

UniProt

P04808

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: E.coli; Immunogen sequence: R162-Cys185 (A) & K26-S53 (B)

Tissue Specificity

Prostate. Not expressed in placenta, decidua or ovary. .

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, serum and plasma (heparin).

Detection Range

78 pg/ml - 5,000 pg/ml

Sensitivity

<10 pg/ml

Function

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)